This hand was played by two friends of mine.
♠ A 3
♥ A 7 6
♦ A K Q 10 3 2
♣ Q 4
♠ K Q 9 5 3
♥ Q J 3
♣ A 9 7 2
The auction started with a big club by North, South bid 1♥, showing 5+ spades and game-forcing values. North bid 2♦ and South bid 2♠. When I talked to him today, he admitted he should have bid 3♣ because he showed six or more spades with the 2♠ call. North rebid diamonds and South now bid his club suit. I'm not sure of the continuation, but the final contract was 6♠.
West led a low spade. You play the ace, then the king and queen. West shows out on the third one, so you have a sure trump loser. How do you play it from here? One thing to think about is the opening lead. Why didn't West fire out a heart, the unbid suit? In other words, if you need the ♥K onside to take 12 tricks, there is an inference that is is on your left, although it's only a clue and not dispositive.
What now? Your novice teammates are counting on you.